Do infants have more extracellular fluid?

Extracellular fluid volume decreases over the first year of life to 30% of TBW and decreases with age thereafter, reaching adult values early in childhood. The relatively high ECF volume in infancy is largely due to the larger interstitial lymph space.

Do infants have more intracellular water than adults?

The total body water (TBW) in humans is distributed in two major compartments. 2/3rd the of TBW is in the intracellular compartment and the other 1/3rd is distributed between interstitial space (75%) and plasma (25%). The total body water is higher in infants and children as compared to the adults.

Do infants have less extracellular fluid?

The extracellular fluid (ECF) represents the main part of TBW and decreases in parallel from 40% in term neonates to adult levels of 20–25% after one year of age. The ICF does not vary much during infancy, from 30% at birth to 40% in adults [1].

Is intracellular fluid more than extracellular?

Extracellular fluid makes up about one-third of body fluid, the remaining two-thirds is intracellular fluid within cells. The main component of the extracellular fluid is the interstitial fluid that surrounds cells.

Why do children have more extracellular fluid?

First, the higher metabolic rate of children requires a greater caloric expenditure, which translates into higher fluid requirements. Secondly, children, especially infants, have a much higher body surface area to weight ratio, and this translates into relatively more water loss from skin compared with adults.

Why do infants have proportionally more water?

Therefore, infants and children require proportionally greater volumes of water than adults to maintain their fluid equilibrium and are more susceptible to volume depletion. Significant fluid losses may occur rapidly, leading to depletion of the intravascular volume.

Why infants have more body water?

Babies and small children have an increased chance of becoming dehydrated because: A greater portion of their bodies is made of water. Children have a high metabolic rate, so their bodies use more water. A child’s kidneys do not conserve water as well as an adult’s kidneys.

What is the relationship between intracellular and extracellular fluids?

Intracellular fluid is present inside the cells while extracellular fluid is present outside the cells. This is the key difference between intracellular and extracellular fluids. Both intracellular and extracellular fluids contain more water.

Why do babies have a larger surface area?

The body contains 2 major fluid compartments: the intracellular fluid (ICF) and the extracellular fluid (ECF). Infants’ and children’s higher body water content, along with their higher metabolic rates and increased body surface area to mass index, contribute to their higher turnover of fluids and solute.

What is the difference between extracellular and intracellular fluid?

Extracellular fluid present outside the cell and intracellular fluid present inside the cell. The total % of the extracellular and intracellular fluid in our body, 2/3 of total body water present in intracellular and 1/3 of total body water present in extracellular fluid. The intracellular and extracellular fluid ratio is totally based on age.

What is the ratio of extracellular and intracellular fluid in human body?

The total % of the extracellular and intracellular fluid in our body, 2/3 of total body water present in intracellular and 1/3 of total body water present in extracellular fluid. The intracellular and extracellular fluid ratio is totally based on age.

What is intracellular fluid (ICF)?

Intracellular Fluid (ICF) The fluid inside of cells, also called the cytoplasm or cytosol, makes up about 60% of the water in the human body, totaling about 7 gallons.

What is extracellular fluid (ECF)?

Extracellular Fluid (ECF) ECFs are any body fluids that are not inside cells. The two main components of ECF are plasma and interstitial fluid (IF). The balance consists of cerebrospinal fluid, lymph, the synovial fluid in the joints, pleural fluid in the pleural cavities (lungs), pericardial fluid around the heart,…