How long are Hemochron cuvettes good for?
Cuvettes are good until the printed expiration date as long as they are kept in the refrigerator. The cuvettes must be kept at room temperature for 60 minutes prior to testing. At room temperature, an unopened pouch is good for 12 weeks.
How do you use Hemochron?
- From the collection syringe dispense exactly 2.0 ml of blood into the test tube.
- Close the flip-top.
- Insert test tube into the Hemochron test well.
- When clot formation is detected, the instrument beeps three times and the test name, clotting time (in seconds) is displayed.
What is a Hemochron?
The Hemochron® Signature Elite is a point-of-care coagulation testing system. When used with the Hemochron® Jr Low Range Activated Clotting Time (ACT-LR) cuvette, it provides a quantitative assay for monitoring heparin anticoagulation during various medical procedures when heparin is used.
What is Hemochron Signature Elite?
The Hemochron® Signature Elite is a point-of-care coagulation testing system. When used with the Hemochron® Jr. Activated Clotting Time Plus (ACT+) cuvette, it provides a quantitative assay for monitoring heparin anticoagulation during various medical procedures when high doses of heparin are used.
How does the Hemochron Signature Elite work?
The HEMOCHRON Signature Elite instrument is a hand-held device. It contains a test chamber which warms a test cuvette to the required temperature, and it performs all operations to measure the clotting time of a whole blood sample after it is placed in the test cuvette and the test is started by the operator.
Who makes Hemochron?
Werfen announced that the GEM Hemochron 100 whole blood hemostasis system received 510(k) clearance by the US Food and Drug Administration (FDA).
What is POCT activated clotting time?
POC | Activated Clotting Time, POC Guidelines for normal Activated Clotting Time without the presence of heparin are 90-120 seconds. After heparinzation, the level of acceptable ACT varies according to the procedure. 1.
What is the antidote for heparin?
Expert opinion: Despite of the low therapeutic index, protamine is the only registered antidote of heparins. The toxicology of protamine depends on a complex interaction of the high molecular weight, a cationic peptide with the surfaces of the vasculature and blood cells.
What is heparin ACT?
The activated clotting time (ACT) is a test that is used primarily to monitor high doses of unfractionated (standard) heparin therapy. Heparin is a drug that inhibits blood clotting (anticoagulant) and is usually given through a vein (intravenously, IV), by injection or continuous infusion.
Is heparin an acid or base?
Heparin is strongly acidic because of its content of covalently linked sulfate and carboxylic acid groups. In heparin sodium, the acidic protons of the sulfate units are partially replaced by sodium ions.
Where is heparin metabolized?
|Metabolism||Sequestered into reticuloendothelial cells and degraded gradually into inactive and renally cleared metabolites.||Mainly metabolized by the liver via desulfation and depolymerization to lower molecular weight fragments, which end up beign either less potent or totally inactive|