What is the antidote of digoxin?

What is the antidote of digoxin?

In the case of severe digoxin intoxication, an antidote digoxin immune Fab (Digibind) is available. Digibind binds and inactivates digoxin.

What are nursing interventions for digoxin toxicity?

An additional nursing intervention to guard against digoxin toxicity is to assess the apical pulse for one full minute before administering digoxin. Hold the next dose and contact the physician if the apical pulse is less than 60 or more than 120 beats per minute.

What is the nurse’s priority when administering digoxin?

A nurse should assess the apical pulse for a full minute before administering digoxin due to its positive inotropic action (it increases contractility, stroke volume, and, thus, cardiac output), negative chronotropic action (it decreases heart rate), and negative dromotropic action (it decreases electrical conduction …

What drug is used for digoxin toxicity?

The primary treatment of digoxin toxicity is digoxin immune fab, which is an antibody made up of anti-digoxin immunoglobulin fragments. This antidote has been shown to be highly effective in treating life-threatening signs of digoxin toxicity such as hyperkalemia, hemodynamic instability, and arrhythmias.

When do you give digoxin antidote?

If acute poisoning and serum digoxin confirmed >10 ng/mL, give empiric dose (10-20 vials). See Evidence for details. Additional considerations for treatment of digoxin toxicity include: Atropine 0.5 mg IV for acute toxicity if bradydysrhythmias or high degree AV block.

Which antidote is used for lead poisoning?

Dimercaprol (British antilewisite [BAL], or 2,3-dimercapto-1-propanol) was the first chelator used in encephalopathic individuals and is the drug of choice for treatment of lead toxicity.

How do you administer digoxin IV?

Administration of digoxin injection: Each dose should be given by intravenous infusion over of 10 – 20 minutes. The total loading dose should be administered in divided doses with approximately half of the total dose given as the first dose and further fractions of the total dose given at intervals of 4 – 8 hours.

Which drug can be used to counteract the digitalis induced ventricular Extrasystoles?

Potassium chloride, lidocaine and diphenylhydantoin are the drugs of choice in the treatment of tachyarrhythmias and ventricular premature beats. Atropine can be used to counteract the vagal effect of digitalis in bradycardia and heart block.

What class is procainamide?

Procainamide is a medication used to manage and treat ventricular arrhythmias, supraventricular arrhythmias, atrial flutter, atrial fibrillation, AV nodal re-entrant tachycardia, and Wolf-Parkinson-White syndrome. It is a Class 1A antiarrhythmic agent.

How is Digibind given?

DIGIBIND, Digoxin Immune Fab (Ovine), is administered by the intravenous route over 30 minutes. It is recommended that it be infused through a 0.22-micron membrane filter to ensure no undissolved particulate matter is administered. If cardiac arrest is imminent, it can be given as a bolus injection.

When do you administer DigiFab?

DigiFab should be administered slowly as an intravenous infusion over at least 30 minutes. If infusion rate-related reactions occur, the infusion should be stopped and re-started at a slower rate. If cardiac arrest is imminent, DigiFab can be given by bolus injection.

How do you teach patients about digoxin toxicity?

Patient/Family Teaching. Teach patient to take pulse and to contact health care professional before taking medication if pulse rate is <60 or >100. Pedi: Teach parents or caregivers that changes in heart rate, especially bradycardia, are among the first signs of digoxin toxicity in infants and children.

How is digoxin used to treat heart arrhythmias?

Treatment of life-threatening arrhythmias may include administration of digoxin immune Fab (Digibind) , which binds to the digitalis glycoside molecule in the blood and is excreted by the kidneys. Do not confuse Lanoxin (digoxin) with levothyroxine or naloxone. High Alert: Digoxin has a narrow therapeutic range.

What should be considered before administering digoxin to a hypokalemic patient?

Before administering initial loading dose, determine whether patient has taken any digoxin in the preceding 2–3 wk. Evaluate serum electrolyte levels (especially potassium, magnesium, and calcium) and renal and hepatic function periodically during therapy. Notify health care professional before giving dose if patient is hypokalemic.

What are the possible medication errors associated with digoxin toxicity?

Medication errors associated with digoxin include miscalculation of pediatric doses and insufficient monitoring of digoxin levels. Have second practitioner independently check original order and dose calculations. For rapid digitalization, initial dose is higher than maintenance dose; 50% of total digitalizing dose is given initially.