What causes a neurofibroma?

What causes a neurofibroma?

The cause of a sporadic neurofibroma is not known, although researchers are exploring the role of trauma. Neurofibromatosis is a genetic disease caused by a mutation in a gene responsible for a protein that regulates nerve tissue growth, and can be inherited.

Can neurofibromas be removed?

There are many ways to remove neurofibromas. Usually a neurofibroma is “excised”, meaning “cut out”, by a scalpel or other means; or they are “destroyed” by electrosurgery. The tumors may also be destroyed (ablated) by desiccation (dehydration or drying), or vaporized using electrosurgery.

How does a neurofibroma start?

Neurofibromatosis is caused by genetic defects (mutations) that either are passed on by a parent or occur spontaneously at conception. The specific genes involved depend on the type of neurofibromatosis: NF1 . The NF1 gene is located on chromosome 17.

How big can a neurofibroma get?

Six or more flat, light brown spots on the skin (“café-au-lait” spots), which are the most common feature of NF1. These multiple birthmarks measure more than 5 millimeters in diameter in children or more than 15 millimeters across in adolescents and adults.

How long can you live with neurofibromatosis?

The life expectancy of a person with NF is approximately 8 years less than that of the general population. Lifetime risks of both benign and malignant tumors are increased in individuals with neurofibromatosis type 1 (NF1).