Are butyrate supplements good for you?
Your body produces less butyrate than other short-chain fatty acids, but it has many health benefits. It is needed for your overall gut health, as well as helping to make energy for some of your gut cells. Plus, it can plug a leaky gut and even help stabilise blood sugar and cholesterol levels.
Which fiber produces most butyrate?
The most abundant of the butyrate producers in the human gut are Eubacterium rectale and Faecalibacterium prausnitzii, both of which are capable of degrading inulin and producing butyrate from it (27).
Does butyrate cause weight gain?

At 5% in the high-fat diet, butyrate increased the calorie content from 58 to 64.4% in the fat. The increase in fat calories may not contribute to our observation of the antiobesity activity for butyrate.
Can butyrate be bad for you?
Their findings now illustrate that butyrate, derived from bacterial fermentation of dietary fibers, is perhaps the most harmful and potent at suppressing the proliferation of stem/progenitor cells in the crypts.
How do I get more butyrate?
What can you do to increase butyrate? The best way to supercharge your gut microbiome to produce butyrate is to eat a high-fibre diet, that includes sufficient sources of resistant starch and pectin. This means eating a diet rich in plant-based foods such as wholegrains, vegetables, fruits, nuts/seeds and legumes.
What are the side effects of butyrate?

If experienced, these tend to have a Less Severe expression i
- a hormone disorder where the body produces high levels of cortisol called Cushing’s syndrome.
- hair loss.
- dry skin.
- skin discoloration.
- blistering of the skin.
- skin irritation.
- high blood sugar.
- skin irritation or rash around the mouth or lips.
How much butyrate should I take?
150–300 mg/day is the most common dosage recommendation for currently available butyric acid products.
What foods increase butyrate?
Will butyrate help me lose weight?
Treatment of obesity with butyrate. After a 5-week treatment with butyrate, the obese mice lost 10.2% of their original body weight, which dropped from 37.6 to 34.4 g (Fig. 7A). In the control group, body weight increased by 15.8% (from 35.9 to 41.6 g) during the same time period.