What is dexpanthenol in nasal spray?

Action. Pharmacology: Spray into the nostrils, Mar Plus 5% Nasal Spray loosens nasal secretions and moistens the dry nasal mucosa, with dexpanthenol additionally promoting the regeneration of damaged epithelial cells.

How long can you use xylometazoline?

Children aged 6-12 years should not use xylometazoline for longer than five days at a time, but adults and children over 12 years of age can use it for up to seven days if needed. Xylometazoline must not be given to children under 6 years of age.

What is the formulation of nasal spray?

Nasal spray formulations may be water-based, hydroalcoholic, nonaqueous, suspensions, or emulsions. A formulation can include diverse excipients, including solvents, mucoadhesive agents, buffers, antioxidants, preservatives, and penetration enhancers (i.e., compounds to improve absorption or penetration).

Are nasal sprays aerosols?

Nasal Spray 1 % Aerosol – Uses, Side Effects, and More.

What is dexpanthenol cream used for?

This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (such as diaper rash, skin burns from radiation therapy). Emollients are substances that soften and moisturize the skin and decrease itching and flaking.

How do you restore nasal mucosa?

Treatments such as antibiotics, nasal douche, steroid, and nasal sprays are commonly being prescribed to patients to eliminate infection, reduce inflammation, and revert the diseased mucosa to normal, functional respiratory epithelium.

Which is better oxymetazoline or xylometazoline?

During the evaluation of nasal resistance and airflow, we did not observe any statistically significant difference between oxymetazoline and xylometazoline (Table 2). The evaluation of nCSAs revealed that xylometazoline seemed to produce better results than oxymetazoline (Figs.

What happens if you use too much xylometazoline?

Symptoms of overdose may include: drowsiness, slow heartbeat, dizziness, fainting. Do not share this medication with others. Use of this container by more than one person may spread infection. There are various nasal decongestants available, many without a prescription.

What is the pH of nasal drops?

The local pH value inside the nasal cavity will have a direct effect on the rate and extent of absorption of drugs; the optimal range for pH value of the nasal spray formulation is suggested to be between 4.5 and 6.5.

Which buffer is used in nasal spray?

Examples of buffer used in nasal spray sodium phosphate, Sodium citrate, citric acid.

What is the difference between intranasal and inhalation?

Intranasal instillation of virus in a liquid suspension (IN) is the most frequently employed method to inoculate small mammalian models with influenza virus, but does not reflect a natural route of exposure. In contrast, inoculation via aerosol inhalation (AR) more closely resembles human exposure to influenza virus.

Is nasal spray considered inhaled?

The dose is delivered by the integral pump components of the container closure system to the lungs by oral inhalation for local and/or systemic effects.