Which HRT is best for osteoporosis?

Tibolone, a selective tissue estrogenic activity regulator (STEAR), is effective in the treatment of vasomotor symptoms, vaginal atrophy and prevention/treatment of osteoporosis with a clinical efficacy similar to that of conventional HRT.

Can you take HRT if you have osteoporosis?

HRT is an effective treatment for menopausal symptoms and offers protection against fractures at both hips and spine. For women affected by osteoporosis aged under 60, HRT has a role to play in the management of osteoporosis.

Can you take HRT with Alendronic acid?

Alendronate seems to be more effective than HRT with respect to changes in BMD, and combining HRT with alendronate might produce a synergistic effect in patients with postmenopausal osteoporosis, especially in the first 2–3 years of the treatment period.

Is Prolia approved for osteopenia?

Prolia isn’t approved to treat osteopenia or arthritis. With osteopenia, your bone mineral density (BMD) is lower than normal. (BMD is a measurement of the amount of minerals such as calcium in your bones.) This means your bones may be weaker than normal.

Can I take HRT at 65?

It is not usually appropriate for women over 60 to be starting HRT but as the WHI study shows, women initiating it over 60 years do not seem to be at increased risk of cardiovascular events or mortality. Many women seek advice on the effects of HRT on sexual activity and desire.

Can you take estrogen for osteoporosis?

Hormone replacement therapy (HRT) — either estrogen alone or a combination of estrogen and progestin — is approved for the prevention and treatment of osteoporosis in women.

Can I take HRT If I have osteoporosis?

Your GP should explain that for women around menopausal age the risk of breaking a bone is low, and HRT reduces this risk further. This benefit only lasts while you are taking HRT but it may last longer if you have taken HRT for a long time. NICE has produced advice about fragility fractures in osteoporosis.

What are the Nice and sign guidelines for osteoporosis management?

These recommendations are based on the National Institute for Health and Care Excellence (NICE) guideline Osteoporosis: assessing the risk of fragility fracture [ NICE, 2012b ] and the Scottish Intercollegiate Guidelines Network (SIGN) guideline Management of osteoporosis and the prevention of fragility fractures [ SIGN, 2015 ].

Which medications are used to treat osteoporotic fractures in postmenopausal women?

In postmenopausal women with at least one severe or two moderate low-trauma vertebral fractures, teriparatide or romosozumab are recommended over oral bisphosphonates. Glucocorticoid treatment is strongly associated with bone loss and increased risk of fractures.

When is bone-protection treatment indicated in the treatment of osteoporosis?

Bone-protection treatment should be started at the onset of glucocorticoid treatment in patients who are at a high risk of fracture. Women aged ≥70 years, or with a previous fragility fracture, or taking large doses of glucocorticoids (prednisolone ≥7.5 mg daily or equivalent) should be considered for bone-protection treatment.